If Excel crashes when saving makes you lose Excel files unsaved, restore Excel by AutoRecover. Run Excel in safe mode to see if it can be accessed successfully. On the 'File' tab, click 'Open'.Click on the location where the spreadsheet is loaded and click 'Browse'. Open 'Control Panel' > click 'Programs and Features' > find 'Microsoft Office" data-type="undefined" target="_blank"> right-click on 'Change'.